Incidence of eNOS gene mutationin Korean patients with coronary artery spasm
Korean Circulation Journal
; : 512-512, 2001.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-139317
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
Coronary artery spasm is an important mechanism in producing myocardial ischemia. But the exact mechanism of the spasm is not well known. We investigated the mutation of endothelial nitric oxide synthase (eNOS) that produce nitric oxide and relationship between eNOS mutation and coronary artery spasm. MATERIALS ANDMETHODS:
Blood were drawn from the patients with angiographically proven coronary artery spasm and normal controls. DNA were extracted and polymerase chain reaction and restriction analysis with Nae I were performed to find T-786--RESULTS:
The prevalence of coronary artery spasm in Chungnam National University Hospital was 19% (125/664). The 85 cases of coronary artery spasm and 131 cases of normal control were compared. The men in spasm group were more prevalent than the women (p<0.0001) and rate of smoking were higher in spasm group (p<0.0001). The T-786--CONCLUSION:
The T-786--
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Smoke
/
Spasm
/
Triglycerides
/
DNA
/
Smoking
/
Polymerase Chain Reaction
/
Cholesterol
/
Incidence
/
Prevalence
/
Myocardial Ischemia
Type of study:
Incidence study
/
Prevalence study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Circulation Journal
Year:
2001
Document type:
Article