The Feasibility of Short Term Prophylactic Antibiotics in Gastric Cancer Surgery
Journal of Gastric Cancer
; : 206-211, 2010.
Article
in En
| WPRIM
| ID: wpr-139719
Responsible library:
WPRO
ABSTRACT
PURPOSE: Most surgeons administer prophylactic antibiotics for 3 to 5 days postoperatively. However, the Center for Disease Control (CDC) guideline recommends antibiotic therapy for 24 hours or less in clean/uncontaminated surgery. Thus, we prospectively studied the use of short term prophylactic antibiotic therapy after gastric cancer surgery. MATERIALS AND METHODS: A total of 103 patients who underwent gastric cancer surgery between October 2007 and June 2008 were prospectively enrolled in a short term prophylactic antibiotics program. One gram of cefoxitin was administered 30 minutes before the incision, and one additional gram was administered intraoperatively for cases with an operation time over 3 hours. Postoperatively, one gram was administered 3 times, every 8 hours. Patients were checked routinely for fever. All cases received open surgery, and the surgical wounds were dressed and checked for Surgical Site Infection (SSI) daily. RESULTS: Of the 103 patients, 15 were dropped based on exclusion criteria (severe organ dysfunction, combined resection of the colon, etc). The remaining 88 patients were included in the short-term program of prophylactic antibiotic use. Of these patients, SSIs were detected in 8 (9.1%) and fever after 2 postoperative days was detected in 11 (12.5%). The incidence of SSIs increased with patient age, and postoperative fever correlated with operation time. CONCLUSIONS: Short term prophylactic antibiotic usage is feasible in patients who undergo gastric cancer surgery, and where there are no grave comorbidities or combined resection.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Stomach Neoplasms
/
Comorbidity
/
Cefoxitin
/
Incidence
/
Prospective Studies
/
Colon
/
Antibiotic Prophylaxis
/
Fever
/
Anti-Bacterial Agents
Type of study:
Guideline
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Journal of Gastric Cancer
Year:
2010
Document type:
Article