Comparison of Tactile DBS and TOF Fade Evaluated Intubation Conditions after Vecuronium Administration / 대한마취과학회지

ABSTRACT

The tactile DBS and TOF fade evaluated intubation conditions under the neuromuscular blockade induced with vecuronium was studied in 40 cases who were ASA 1 or 2 adult patients. All patients were premedicated with glycopyrrolate 0.2 mg and hydroxyzine 1 mg/kg 1 hour before induction, and inducted with thiopental sodium 5 mg/kg, O2-N2O(50%) and enflurane(2%). The patients were randomly divided to two groups according to the mode of nerve stimulation TOF group(n=20) and DBS group(n=20). Neuromuscular blockade was monitored by stimulation of the ulnar nerve at the wrist using INNERVATOR(fisher & Paykel Co.). For both stimulation patterns the frequencies of manually detectable fade in the response to stimulation were undetectable fade in both group after vecuronium(0.1mg/kg) injection intravenousely. The response of tracheal intubation was appreciated based on vocal cord reflex, coughing or barking, and jaw relaxation. The time from administration of vecuronium to undetectable fade was 214.2+/-68.5 in TOF group and 250.2+/-51.8 in DBS group but no statistical difference. In addition, intubation conditions in DBS group were little better than in TOF group but it was also no significant. Conclusively, there was no different between TOF and DBS fade to evaluate the intubation conditions under the neuromuscular blockade induced with vecuronium.