Serotype and Nucleotide Analysis of Human Rotavirus Isolates in Korea
Journal of the Korean Society of Virology
; : 75-86, 1999.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-142042
Responsible library:
WPRO
ABSTRACT
Rotaviruses belong to Reoviridae causes diarrhea in human beings as well as domestic animals. This study was conducted to see what type of human rotaviruses are distributed in Seoul and Kyung-gi province. Twenty two of 81 patients showed rotavirus positive with diagnostic kit and RNA electropherosis. We isolated all of rotaviruses from the patients. Electropherotypes of 22 isolates showed 4232 patters whereas those migration patterns were long type. All of those isolates belonged to group 4. Twenty out of 22 isolates reacted with monoclonal antibodies specific to G1, P1A and subgroup II, whereas rest of them, 4-29 and K-30 reacted with subgroup I specific monoclonal antibody. The nucleotide sequence of an isolate K-21 showed 98~100% and 90~96% homologies with those of Wa and KU strain, respectively.
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Diarrhea
/
Neglected Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Reoviridae
/
RNA
/
Base Sequence
/
Rotavirus
/
Diarrhea
/
Seoul
/
Korea
/
Animals, Domestic
/
Antibodies, Monoclonal
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Society of Virology
Year:
1999
Document type:
Article