A Case of Congenital Hypopituitarism with Anterior Pituitary Hypoplasia and Ectopic Posterior Pituitary Gland
Journal of the Korean Pediatric Society
; : 1746-1750, 1999.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-143038
Responsible library:
WPRO
ABSTRACT
The pituitary gland develops from two different parts of the brain. The anterior pituitary gland originates from the Rathke pouch and the posterior one from the infundibulum. Therefore, the pathologic findings of congenital hypopituitarism can be different in each case. Congenital hypopituitarism is a rare disorder. The characteristic clinical features of the affected newborns are prolonged jaundice, persistent or recurrent hypoglycemia without hyperinsulinism and microphallus. Their genitalia are usually underdeveloped and sexual maturation may be delayed or absent. In adulthood, patients retain childish feature, short stature with normal body proportion. We experienced a case of congenital hypopituitarism in a 12-year-old female patient with short stature and delayed sexual maturation(Tanner stageI). The endocrinological studies revealed growth hormone, FSH, LH and TSH deficiencies. Magnetic resonance imaging indicated a hypoplastic anterior pituitary and an ectopic posterior pituitary gland located within the tuber cinereum of the hypothalamus.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pituitary Gland
/
Pituitary Gland, Anterior
/
Pituitary Gland, Posterior
/
Sexual Maturation
/
Tuber Cinereum
/
Brain
/
Growth Hormone
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Magnetic Resonance Imaging
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Genitalia
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Hyperinsulinism
Limits:
Child
/
Female
/
Humans
/
Infant, Newborn
Language:
Korean
Journal:
Journal of the Korean Pediatric Society
Year:
1999
Document type:
Article