Primary Osteosarcoma of the Breast: A case report

ABSTRACT

Primary osteosarcoma of the breast is very rare. There have been no previously reported cases in Korea. In this paper, a case of primary osteosarcoma of the breast is reported. It should be distinguished from a carcinoma with extensive osseous metaplasia. Immunohistochemical and ultrastructural studies proved that the lesion, in the absence of epithelial differentiation, was a primary osteosarcoma of the breast rather than a carcinoma with extensive osseous metaplasia. Diagnostic aspects and treatment are discussed and a literature review is given.