A Clinical Analysis of Gastrointestinal Stromal Tumors in Small Intestine: Comparison of Bleeding and Non-bleeding Group
Intestinal Research
; : 113-119, 2013.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-147341
Responsible library:
WPRO
ABSTRACT
BACKGROUND/AIMS:
Gastrointestinal stromal tumors (GIST) in the small intestine are rare and can cause bleeding. The study investigated the clinical characteristics of GIST in the small intestine and to determine the factors related to gastrointestinal bleeding.METHODS:
We retrospectively evaluated the clinical outcomes of 22 patients with small bowel GIST who were pathologically diagnosed at Gangneung Asan Hospital between March 1997 and August 2012.RESULTS:
The median age was 63.5 (38-82) years. Nine patients (40.9%) had gastrointestinal bleeding, five patients (22.7%) had abdominal pain, two patients (9%) had palpable mass. The site of tumor was the duodenum in nine cases (40.9%), jejunum in 7 cases (31.8%), and ileum in six cases (27.3%). Most patients underwent small bowel resection or wedge resection but three patients underwent pancreaticoduodenectomy. Tumor size ranged from 1.6 to 19 cm (median 6.5 cm). The median mitotic rate was 2 (0-50)/50 high power fields (HPF). The median mitotic rate was 2 (0-50)/50 HPF. Five patients (25%) showed recurrence. Gender, aspirin or warfarin use, size and mitotic index of tumor, hospital stay, recurrence and survival were not significantly different between bleeding and non-bleeding group. Bleeding group showed older age, proximal location in small intestine and mucosal ulceration significantly.CONCLUSIONS:
Small bowel GISTs with bleeding were marked by older age, mucosal ulceration and location of proximal small bowel (duodenum and jejunum) rather than distal small bowel (ileum).
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Ulcer
/
Warfarin
/
Abdominal Pain
/
Aspirin
/
Retrospective Studies
/
Pancreaticoduodenectomy
/
Gastrointestinal Stromal Tumors
/
Duodenum
/
Hemorrhage
Type of study:
Observational study
Limits:
Humans
Language:
Korean
Journal:
Intestinal Research
Year:
2013
Document type:
Article