Risk Factors for Long-term Outcomes after Initial Treatment in Hepatolithiasis
Journal of Korean Medical Science
; : 1627-1631, 2013.
Article
in En
| WPRIM
| ID: wpr-148466
Responsible library:
WPRO
ABSTRACT
Hepatobiliary complications, such as stone recurrence, recurrent cholangitis, liver abscess, secondary biliary cirrhosis, and cholangiocarcinoma may occur after treatment for hepatolithiasis. However, few previous studies have addressed the risk factors and long-term outcomes after initial treatment. Eighty-five patients with newly diagnosed hepatolithiasis, actively treated for hepatolithiasis, constituted the cohort of this retrospective study. Patients were treated by hepatectomy or nonoperative percutaneous transhepatic cholangioscopic lithotomy. Long-term complications, such as recurrent cholangitis, liver abscess, secondary biliary cirrhosis, and cholangiocarcinoma, and their relationships with clinical parameters were analyzed. The mean follow-up period was 57.4 months. The overall hepatobiliary complication rate after the treatment was 17.6%. Multivariate analysis of suspected risk factors showed that complications were associated with age (HR, 1.046; CI, 1.006-1.089), bile duct stricture (HR, 4.894; CI, 1.295-18.495), and residual stones (HR, 3.482; CI, 1.214-9.981). In conclusion, several long-term hepatobiliary complications occur after hepatolithiasis treatment, and regular observation is necessary in patients with concomitant biliary stricture or residual stones.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Bile Ducts, Intrahepatic
/
Biliary Tract
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Biliary Tract Surgical Procedures
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Gallstones
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Cholestasis, Intrahepatic
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Retrospective Studies
/
Risk Factors
/
Treatment Outcome
/
Endoscopy
/
Hepatectomy
Type of study:
Etiology_studies
/
Observational_studies
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Risk_factors_studies
Limits:
Adult
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Aged
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Aged80
/
Female
/
Humans
/
Male
Language:
En
Journal:
Journal of Korean Medical Science
Year:
2013
Document type:
Article