Optimization of Subtraction Brain Perfusion SPECT with Basal / Acetazolamide Consecutive Acquisition / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
; : 330-338, 1997.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-14908
Responsible library:
WPRO
ABSTRACT
This study investigated the method to adjust acquisition time(a) and injection dose(i) to make the best basal and subtraction images in consecutive SPECT. Image quality was assumed to be mainly affected by signal to noise ratio(S/N). Basal image was subtracted from the second image consecutively acquired at the same position. We calculated S/N ratio in basal SPECT images(S1/N1) and subtraction SPECT images(Ss/Ns) to find a(time) and i(dose) to maximize S/N of both images at the same time. From phantom images, we drew the relation of image counts and a(time) and i(dose) in our system using fanbeam-high-resolution collimated triple head SPECT. Noise by imaging process depended on Poisson distribution. We took maximum tolerable duration of consecutive acquisition as 30 minutes and maximum injectible dose as 1,850MBq(50 mCi)(sum of two injections) per study. Counts of second-acquired image(S2), counts(Ss) and noise(Ns) of subtraction SPECT were as follows. C1 was the coefficient of measurement with our system.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Perfusion
/
Brain
/
Tomography, Emission-Computed, Single-Photon
/
Signal-To-Noise Ratio
/
Head
/
Acetazolamide
/
Noise
Language:
Korean
Journal:
Korean Journal of Nuclear Medicine
Year:
1997
Document type:
Article