Clinical Guidelines for the Diagnosis and Treatment of Cushing's Disease in Korea
Endocrinology and Metabolism
; : 7-18, 2015.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-150125
Responsible library:
WPRO
ABSTRACT
Cushing's disease (CD) is a rare disorder characterized by the overproduction of adrenocorticotropic hormone due to a pituitary adenoma that ultimately stimulates excessive cortisol secretion from the adrenal glands. Prior to the detection of pituitary adenomas, various clinical signs of CD such as central obesity, moon face, hirsutism, and facial plethora are usually already present. Uncontrolled hypercortisolism is associated with metabolic, cardiovascular, and psychological disorders that result in increased mortality. Hence, the early detection and treatment of CD are not only important but mandatory. Because its clinical manifestations vary from patient to patient and are common in other obesity-related conditions, the precise diagnosis of CD can be problematic. Thus, the present set of guidelines was compiled by Korean experts in this field to assist clinicians with the screening, diagnoses, and treatment of patients with CD using currently available tests and treatment modalities.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Target 3.4: Reduce premature mortality due to noncommunicable diseases
/
Brain and Nervous System Cancers
/
Endocrine System Diseases
/
Skin Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Pituitary Neoplasms
/
Corticotropin-Releasing Hormone
/
Hydrocortisone
/
Mass Screening
/
Mortality
/
Petrosal Sinus Sampling
/
Adrenal Glands
/
Adrenocorticotropic Hormone
/
Cushing Syndrome
/
Pituitary ACTH Hypersecretion
Type of study:
Diagnostic study
/
Practice guideline
/
Prognostic study
/
Screening study
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Endocrinology and Metabolism
Year:
2015
Document type:
Article