A Case of Hypomelanosis of Ito with Hemimegalencephaly
Journal of the Korean Pediatric Society
; : 1137-1141, 2000.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-154007
Responsible library:
WPRO
ABSTRACT
Hypomelanosis of Ito is a congenital neurocutaneous syndrome with a particular pattern of streaks, patches and swirling hypopigmentation over variable portions of the body surface. Multiple extracutaneous abnormalities involving the central nervous system, musculoskeletal structures and the eyes occur in over two-thirds of the cases. This report describes a patient with typical unilateral cutaneous lesions associated with extracutaneous features, including hypertrophy of the cerebral hemisphere contralateral to the cutaneous hypopigmentation. Chromosomal analysis of fibroblasts of depigmented skin obtained from the patients showed mosaicism.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Skin
/
Central Nervous System
/
Hypopigmentation
/
Neurocutaneous Syndromes
/
Cerebrum
/
Malformations of Cortical Development
/
Fibroblasts
/
Hypertrophy
/
Mosaicism
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Pediatric Society
Year:
2000
Document type:
Article