Comparison of Primary Vascular Dysregulation in Normal Tension Glaucoma and Primary Open Angle Glaucoma
Journal of the Korean Ophthalmological Society
; : 393-400, 2010.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-155248
Responsible library:
WPRO
ABSTRACT
PURPOSE:
To evaluate the clinical symptoms or signs of primary vascular dysregulation (PVD) in patients with normal tension glaucoma (NTG) and primary open-angle glaucoma (POAG).METHODS:
From June 2008 to June 2009, we administered questionnaires to patients with glaucoma. The questionnaire was composed of 11 items, and the questionnaire results were compared between patients with NTG and POAG. NTG patients were subdivided by age(criterion 55 years) and perimetric mean deviation (criterion -6dB).RESULTS:
We detected a significant increase in hypotension (p=0.036) in NTG patients (n=133), compared to POAG patients (n=68). Migraines and emotional stress were more frequent in younger patients (55 years) with NTG (27.5%, 42.9%, p=0001). The frequency of drug sensitivity and systemic vasospasm is higher in older patients with NTG (28.6%, 17.4%) than younger patients with NTG (12.9%, 4.9%) but the rate of systemic vasospasm is much higher in younger patients, compared to the prevalence in the general Korean population. In patients with moderate and advanced NTG, hypotension is highly prevalent (p=0.018).CONCLUSIONS:
Hypotension is a greater risk factor for NTG than for POAG. Indeed, vascular factors may be correlated with NTG, especially in younger patients with moderate, advanced visual field defects.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Stress, Psychological
/
Visual Fields
/
Glaucoma
/
Glaucoma, Open-Angle
/
Prevalence
/
Surveys and Questionnaires
/
Risk Factors
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Low Tension Glaucoma
/
Hypotension
/
Migraine Disorders
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2010
Document type:
Article