Secondary Prophylaxis of Docetaxel Induced Diarrhea with Loperamide: Case Report
Journal of Korean Medical Science
; : 1549-1551, 2013.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-155942
Responsible library:
WPRO
ABSTRACT
Diarrhea is a common adverse event of docetaxel with 20%-40% of incidence and severe diarrhea occurs in 5%-6%. Several treatment guidelines for chemotherapy induced diarrhea (CID) exist, however the prophylaxis for that is not well known. We describe a new prophylactic approach for the CID with loperamide. A 72-yr-old male patient with stage IV non-small-cell lung cancer developed diarrhea repeatedly after docetaxel-cisplatin chemotherapy. His diarrhea persisted despite treatment including loperamide and fasting. However, the diarrhea was successfully prevented when loperamide was given before and after the chemotherapy. To our knowledge, this is the first report of prophylactic approach for the CID with loperamide.
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Diarrhea
/
Neglected Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Tomography, X-Ray Computed
/
Cisplatin
/
Carcinoma, Non-Small-Cell Lung
/
Taxoids
/
Diarrhea
/
Drug Therapy, Combination
/
Loperamide
/
Lung Neoplasms
/
Neoplasm Staging
Type of study:
Practice guideline
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2013
Document type:
Article