A Case of Bilateral Macronodular Adrenal Hyperplasia with Cushing's Syndrome Treated by Unilateral Adrenalectomy / 대한내분비학회지
Journal of Korean Society of Endocrinology
; : 596-602, 2002.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-155996
Responsible library:
WPRO
ABSTRACT
In order to differentiate the causes of Cushing's syndrome; whether it is pituitary or adrenal-dependent, a high dose dexamethasone suppression test is usually performed but this does not always correlated with the imaging diagnosis. We report a case of bilateral macronodular adrenal hyperplasia, which was thought to be independent to adrenocorticotrophin (ACTH) stimulation. At first we thought it was pituitary-dependent Cushing's syndrome, due to its suppression by high dose dexamethasone. However, we found no abnormal findings on the brain sella magnetic resonance image (MRI). A significant finding, however, we found bilateral adrenal masses on the abdominal computed tomography (CT). We performed percutaneous selective adrenal venous sampling (PSAVS), and confirmed hypercortisolism of the left adrenal mass only. Therefore, we decided to remove the left adrenal gland to preserve the residual function of the right adrenal gland. After the left adrenalectomy, the patient became normotensive, and their buffalo hump disappeared, and her 24 hour urinary free cortisol level returned to normal.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Brain
/
Buffaloes
/
Dexamethasone
/
Hydrocortisone
/
Adrenal Glands
/
Adrenalectomy
/
Cushing Syndrome
/
Diagnosis
/
Hyperplasia
Type of study:
Diagnostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of Korean Society of Endocrinology
Year:
2002
Document type:
Article