Kidney Transplantation from a Donor Following Cardiac Death Supported with Extracorporeal Membrane Oxygenation
Journal of Korean Medical Science
; : 115-119, 2012.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-156446
Responsible library:
WPRO
ABSTRACT
To expand the donor pool, organ donation after cardiac death (DCD) has emerged. However, kidneys from DCD donors have a period of long warm ischemia between cardiac arrest and the harvesting of the organs. Recently, we used extracorporeal membrane oxygenation (ECMO) to minimize ischemic injury during 'no touch' periods in a Maastricht category II DCD donor and performed two successful kidney transplantations. The kidneys were procured from a 49-yr-old male donor. The warm ischemia time was 31 min, and the time of maintained circulation using ECMO was 7 hr 55 min. The cold ischemia time was 9 hr 15 min. The kidneys were transplanted into two recipients and functioned immediately after reperfusion. The grafts showed excellent function at one and three months post-transplantation; serum creatinine (SCr) levels were 1.0 mg/dL and 0.8 mg/dL and the estimated glomerular filtration rates (eGFR) were 63 mL/min/1.73 m2 and 78 mL/min/1.73 m2 in the first recipient, and SCr levels were 1.1 mg/dL and 1.0 mg/dL and eGFR were 56 mL/min/1.73 m2 and 64 mL/min/1.73 m2 in the second recipient. In conclusion, it is suggested that kidney transplantation from a category II DCD donor assisted by ECMO is a reasonable modality for expanding donor pool.
Full text:
Available
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Kidney, Renal Pelvis and Ureter Cancer
Database:
WPRIM (Western Pacific)
Main subject:
Organ Preservation
/
Potassium Chloride
/
Procaine
/
Time Factors
/
Tissue Donors
/
Extracorporeal Membrane Oxygenation
/
Retrospective Studies
/
Kidney Transplantation
/
Death
/
Glomerular Filtration Rate
Type of study:
Observational study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2012
Document type:
Article