Characterization of canine oral papillomavirus by histopathological and genetic analysis in Korea
Journal of Veterinary Science
; : 21-25, 2010.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-160877
Responsible library:
WPRO
ABSTRACT
In August 2008, forty dogs out of 400 developed oral warts in a breeding farm in Korea. Canine oral papilloma infection is a common disease in dogs. However, there has been no report of an outbreak of canine oral papillomavirus (COPV) in a group of dogs or in dog breeding farms in Korea, and the genetic analysis of COPV in Korea has yet to be performed. This study diagnosed canine oral papilloma from the oral samples of these dogs based on histopathological examination and immunohistochemistry. Polymerase chain reaction was applied to amplify the corresponding products using pre-existing primer sets for COPV and a universal human papillomavirus targeting L1 gene. Further genetic analysis of the major viral capsid gene L1 confirms the sequences of Korean COPV, which shows a close relationship to previously reported COPV. This study describes the histopathological and immunohistochemical characteristics of canine oral papilloma in a group of breeding dogs in Korea and discloses the complete L1 gene sequences of Korean COPV.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
DNA, Viral
/
Immunohistochemistry
/
Molecular Sequence Data
/
Base Sequence
/
Polymerase Chain Reaction
/
Disease Outbreaks
/
Sequence Analysis, DNA
/
Papillomavirus Infections
/
Capsid Proteins
/
Dog Diseases
Limits:
Animals
Country/Region as subject:
Asia
Language:
English
Journal:
Journal of Veterinary Science
Year:
2010
Document type:
Article