Diagnostic Noninvasive Tests for Coronary Artery Disease in Chronic Renal Failure Patients / 대한신장학회잡지
Korean Journal of Nephrology
; : 407-413, 2005.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-165154
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
As ischemic heart disease is the major cause of death in chronic renal failure patients, screening tests are clinically important. Although coronary angiography is considered the gold standard for the diagnosis of coronary artery disease, other noninvasive tests are usually used to avoid this potentially dangerous and costly procedure.METHODS:
We retrospectively determined the sensitivity, specificity, and positive and negative predictive values for electrocardiography, echocardiography, cardiac enzyme determination, and Technetium 99m tetrofosmin (TF) single photon emission computed tomography (SPECT) in 61 chronic renal failure patients who underwent coronary angiography.RESULTS:
Nineteen patients (31.1%) were undergoing chronic hemodialysis, seven patients (11.4%) were undergoing peritoneal dialysis, and thirty five patients (57.3%) were undergoing conservative treatment. 99mTc SPECT had a sensitivity of 96% and specificity of 19%. Although echocardiography and tronponin-T had a relatively lower sensitivity of 69 % and 56% than 99mTc SPECT, they had a higher specificity of 63% and 63%, respectively. 99mTc SPECT had the highest sensitivity of 88% and echocardiography had the highest specificity of 78% in renal replacement group. 99mTc SPECT had the highest sensitivity of 100% and Troponin T had the highest specificity of 71% in conservative treatment group.CONCLUSION:
Noninvasive test for coronary artery disease in patients with chronic renal failure, especially 99mTc SPECT is of limited value because of their low specificity, so echocardiography and troponin T may helpful for diagnosing coronary artery disease.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Target 3.4: Reduce premature mortality due to noncommunicable diseases
/
Cardiovascular Disease
/
Chronic Kidney Disease
/
Ischemic Heart Disease
/
Kidney, Renal Pelvis and Ureter Cancer
Database:
WPRIM (Western Pacific)
Main subject:
Troponin
/
Coronary Artery Disease
/
Echocardiography
/
Tomography, Emission-Computed, Single-Photon
/
Mass Screening
/
Retrospective Studies
/
Cause of Death
/
Sensitivity and Specificity
/
Renal Dialysis
/
Peritoneal Dialysis
Type of study:
Diagnostic study
/
Observational study
/
Screening study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2005
Document type:
Article