Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trial
Journal of Veterinary Science
; : 549-554, 2016.
Article
in En
| WPRIM
| ID: wpr-167763
Responsible library:
WPRO
ABSTRACT
This study was conducted to evaluate the effects of cetirizine in dogs with atopic dermatitis (AD) while fulfilling Favrot's diagnostic clinical criteria. Dogs received either 3 mg/kg cetirizine (n = 27), or a placebo (n = 23) orally once daily for 14 days in a randomized, double blind, placebo-controlled study, without concomitant medication. The effects were evaluated using a pruritus visual analog scale at the start (day 0) and at day 14. After 14 days, cetirizine clearly had no effect on the pruritus in dogs with chronic AD, and there was no significant difference between groups. These findings indicated that cetirizine (and likely H1 histamine receptor antagonists in general) should not be recommended for the control of pruritus in dogs with long term allergies.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Pruritus
/
Receptors, Histamine
/
Cetirizine
/
Dermatitis, Atopic
/
Visual Analog Scale
/
Hypersensitivity
Limits:
Animals
Language:
En
Journal:
Journal of Veterinary Science
Year:
2016
Document type:
Article