Effects of Sesame Oil on the Reproductive Parameters of Diabetes Mellitus-Induced Male Rats
The World Journal of Men's Health
; : 141-149, 2013.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-172358
Responsible library:
WPRO
ABSTRACT
PURPOSE:
The purpose of the present study was to investigate the effect of sesame oil on the reproductive parameters of diabetic male Wistar rats. MATERIALS ANDMETHODS:
The adult male rats in a split plot design were divided into normal (n=10), normal 5% (n=5; 5% sesame oil enriched diet), diabetic (Streptozocin induced diabetes; n=9), diabetic 5% (n=9; 5% sesame oil enriched diet), and diabetic 10% (n=9; 10% sesame oil enriched diet) groups. Diet supplementation continued for 56 days.RESULTS:
Sesame oil supplementation did not reduce the plasma glucose concentration of rats in the diabetic groups (p>0.05). The total spermatogonia, spermatocytes, Leydig cells/tubule, and the germ cell to Sertoli cell ratio were lower in the diabetic rats than the normal ones (p<0.05), and with the exception of spermatogonia counts, these values improved by the addition of sesame oil to the diet (p<0.05). The sperm progressive motility and viability were lower in the diabetic rats (p<0.05) and sesame oil supplementation did not improve them. Incorporation of sesame oil into the diet improved the plasma testosterone concentration of the diabetic rats in a dose-dependent manner (p<0.05).CONCLUSIONS:
In summary, sesame oil supplementation improved the reproductive parameters of diabetic rats at the levels of the testicular microstructure and function, but was not effective in protecting the epididymal sperm.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Spermatocytes
/
Spermatogonia
/
Spermatozoa
/
Testis
/
Testosterone
/
Sesame Oil
/
Sesamum
/
Diabetes Mellitus
/
Diet
/
Germ Cells
Limits:
Animals
Language:
English
Journal:
The World Journal of Men's Health
Year:
2013
Document type:
Article