Clinical Efficacy and Safety of Gepefrin in the Treatment of Hypotension
Korean Circulation Journal
; : 307-312, 1994.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-174993
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
The proper management of the patients with hypotention remains a difficult clinical problem. This study was designed to evaluate the efficacy and safety of gepefrin in the treament of symptomatic hypotensive patients in outpatient clinic of university hospital.METHODS:
Thirty milligrams of Gepefrin was given twice daily for 4 weeks in 30 patients with hypotension(6 males, 24 females ; 23-60 years of age). Blood pressure, heart rate, subjective symptoms and side effects were checked before medication and at the end of 1st, 2nd, 3rd, 4th week of medication.RESULTS:
1) Grpefrin increased sitting systolic blood pressure significantly(p<0.05) by the end of 1st week and thereafter. 2) Hypotensive symptoms were improved in 76% of hypotensive patients and overall rate of usefulness was 70%. 3) Heart rate did not change significantly. 4) One patient complained of loose bowel movement and another one, of anorexia among 30 study patients and all laboratory parameters were within normal limits before and after drug treatment, thus the rate of safety was 93%.CONCLUSION:
Results from this study suggests that gepefrin 60mg daily increases the blood pressure mildly and improves the symptoms moderately in symptomatic hypotensive patients.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Quality of Life
/
Blood Pressure
/
Anorexia
/
Ambulatory Care Facilities
/
Heart Rate
/
Hypotension
Aspects:
Patient-preference
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
Korean Circulation Journal
Year:
1994
Document type:
Article