Vertically Transmitted Severe Coxsackievirus B Infection in Four Preterm Twins Presented / 대한주산의학회잡지
Korean Journal of Perinatology
; : 315-321, 2013.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-177246
Responsible library:
WPRO
ABSTRACT
During summer and fall months (from June to November), enteroviral infection is more common than group B streptococcal infection or herpes simplex viral infection in neonates. Enteroviruses are divided into polioviruses, coxsackieviruses A, coxsackieviruses B, and echoviruses. Enteroviruses can cause a wide spectrum of acute illnesses ranging from non-specific febrile illness, upper respiratory tract infection or gastroenteritis, to severe diseases such as myocarditis, and encephalitis. Coxsackieviruses B are important neonatal pathogens, which can cause meningoencephalitis, disseminated intravascular coagulopathy, and cardiomyopathy. Transplacental transmission of coxsackievirus or perinatal transmission by inhalation or swallowing of cervical secretion or feces during delivery causes more severe diseases than postnatal transmission by horizontal transmission in nursery or neonatal intensive care unit, due to larger load of viruses. Four preterm infants had severe coxsackieviral B infection with thrombocytopenia, meningitis, disseminated intravascular coagulopathy, and myocarditis within seven days of age during this June. Coxsackieviruses B were detected from their feces, cerebrospinal fluid, and blood. Viruses might be transmitted prenatally through placenta from mother to fetus, which caused severe disease. Coxsackieviruses B infections have to be considered in the neonates with sepsis-like illness during summer and fall months, or enteroviral seasons.
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
WPRIM (Western Pacific)
Main subject:
Placenta
/
Respiratory Tract Infections
/
Seasons
/
Streptococcal Infections
/
Thrombocytopenia
/
Infant, Premature
/
Intensive Care, Neonatal
/
Cerebrospinal Fluid
/
Inhalation
/
Enterovirus
Limits:
Humans
/
Infant, Newborn
Language:
Korean
Journal:
Korean Journal of Perinatology
Year:
2013
Document type:
Article