Vitamin D Deficiency in Breastfed Infants / 대한소아내분비학회지
Journal of Korean Society of Pediatric Endocrinology
; : 158-162, 2008.
Article
in Ko
| WPRIM
| ID: wpr-180293
Responsible library:
WPRO
ABSTRACT
PURPOSE: Vitamin D deficiency is a public health problem in many countries. There has been a reappearance of rickets from vitamin D deficiency in recent decades as a result of multiple factors. One of the factors is breast feeding. The purpose of this study was to describe the clinical presentation of rickets in breastfed infants. METHODS: Retrospective review of patients presenting to Ajou University hospital between 2003 and 2008 with rickets caused by vitamin D deficiency during breast feeding. RESULTS: Seventeen patients (10 boys and 7 girls) were diagnosed with vitamin D deficiency. There were six in the asymptomatic and eleven in the symptomatic patients. The mean age of the patients was 8.5+/-0.5 months. The mean 25-hydroxycholecalciferol was 3.55+/-1.88 ng/mL. 25-hydroxycholecalciferol levels were below 5 ng/mL in 13 patients. The mean serum alkaline phosphatase was 765.53+/-563.9 IU/L, the mean intact parathyroid hormone was 231.6+/-225.7 pg/mL. All except 3 patients were showed cupping and fraying of metaphysis. CONCLUSION: Breast feeding is associated with increased risk of rickets. We recommend vitamin D supplementation of all breastfed infants to prevent rickets. Supplementation should begin within the first 2 months of life. Also, we hope to initiate further research and debate about guideline of vitamin D supplementation
Key words
Full text:
1
Database:
WPRIM
Main subject:
Parathyroid Hormone
/
Rickets
/
Vitamin D
/
Vitamin D Deficiency
/
Vitamins
/
Breast Feeding
/
Calcifediol
/
Public Health
/
Retrospective Studies
/
Alkaline Phosphatase
Type of study:
Guideline
/
Observational_studies
Aspects:
Determinantes_sociais_saude
Limits:
Humans
/
Infant
Language:
Ko
Journal:
Journal of Korean Society of Pediatric Endocrinology
Year:
2008
Document type:
Article