Living Donor Exchange Program for Adult Living Donor Liver Transplantation: Preliminary Experience at the Asan Medical Center, Korea / 대한이식학회지
The Journal of the Korean Society for Transplantation
; : 92-96, 2008.
Article
in Ko
| WPRIM
| ID: wpr-180614
Responsible library:
WPRO
ABSTRACT
PURPOSE: When performing donor screening for living donor liver transplantation (LDLT) for an adult patient with end- stage liver disease, ABO blood group incompatibility is the most common cause of donor exclusion. To cope with this problem without performing ABO-incompatible LDLT, living donor exchange program has been maintained at the Asan Medical Center, Seoul, Korea since September 2003. Here we introduce the clinical experience of 6 cases of adult LDLT allocated by living donor exchange program. METHODS: From February, 1997 to December 2006. 1208 cases of adult LDLT were performed in our institution. Among them, there were 6 cases allocating through donor exchange program to avoid ABO blood group mismatching. Three sets of 2 donor-recipient combination pairs were made after direct one-to-one donor-recipient matching. RESULTS: Two sets of donor exchange LDLT were performed on elective surgery basis, but one in emergency situation. Two living donors and 2 recipients underwent LDLT operations at the same time at the same institution. All 6 living donors recovered well. All of the 6 recipients are doing well to date although 1 recipient had undergone prolonged intensive care for surgical complications. There was no emotional or psychological conflict related to donor exchange program. CONCLUSION: This is the world-first report on donor exchange adult LDLT. Although this is a preliminary report with only 3 sets, donor exchange program for adult LDLT appears to be a feasible modality to promote LDLT. We believe it can be applicable to a wider population of LDLT after widespread consensus formation.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Phosphatidylethanolamines
/
Tissue Donors
/
Blood Group Incompatibility
/
Liver Transplantation
/
Living Donors
/
Critical Care
/
Consensus
/
Donor Selection
/
Emergencies
/
Korea
Type of study:
Guideline
Limits:
Adult
/
Humans
Country/Region as subject:
Asia
Language:
Ko
Journal:
The Journal of the Korean Society for Transplantation
Year:
2008
Document type:
Article