Usefulness of Delta Neutrophil Index to Predict 30-day Mortality in Patients with Mechanical Bowel Obstruction
Journal of the Korean Society of Emergency Medicine
; : 403-412, 2017.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-180943
Responsible library:
WPRO
ABSTRACT
PURPOSE:
Mechanical bowel obstruction (MBO) is a common emergency problem resulting in high morbidity and mortality. The delta neutrophil index (DNI), reflecting the fraction of circulating immature granulocytes, is associated with increased mortality in patients with infection and/or systemic inflammation. This study was conducted to investigate the relationship between DNI and 30-day mortality in patients with MBO.METHODS:
We retrospectively identified consecutive patients (>18 years old) with MBO admitted to the emergency department from January 1, 2013 to April 30, 2015. The diagnosis of MBO was confirmed using clinical and radiological findings. The DNI was determined on each day of hospitalization. The outcome of interest was the 30-day mortality and the prognostic value of DNI for 30-day mortality was ascertained by Cox proportional hazards model analysis.RESULTS:
A total of 518 patients with MBO were included in this study. According to multivariate Cox proportional hazard models, higher DNI at admission (hazard ratio [HR], 1.080; 95% confidence interval [CI], 1.036-1.126; p1.9% on admission (HR, 9.410; 95% CI, 2.671-33.145; p<0.001) was associated with increased 30-day mortality. Furthermore, the accuracy of DNI for predicting 30-day mortality was superior to that of other parameters.CONCLUSION:
The DNI can be measured rapidly and simply on emergency department admission without additional cost or time burden. Increased DNI values are associated with 30-day mortality in patients with MBO.
Full text:
Available
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Other Blood Disorders
Database:
WPRIM (Western Pacific)
Main subject:
Proportional Hazards Models
/
Retrospective Studies
/
Mortality
/
Diagnosis
/
Emergencies
/
Emergency Service, Hospital
/
Granulocytes
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Hospitalization
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Inflammation
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Neutrophils
Type of study:
Diagnostic study
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Observational study
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Prognostic study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Society of Emergency Medicine
Year:
2017
Document type:
Article