Burkholderia Sepsis in Children as a Hospital-Acquired Infection
Yonsei Medical Journal
; : 97-102, 2016.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-186117
Responsible library:
WPRO
ABSTRACT
PURPOSE:
Hospital-acquired Burkholderia cepacia (B. cepacia) infection are not commonly recorded in patients without underlying lung disease, such as cystic fibrosis and chronic granulomatous disease. However, in 2014, B. cepacia appeared more frequently in pediatric blood samples than in any other year. In order to access this situation, we analyzed the clinical characteristics of B. cepacia infections in pediatric patients at our hospital. MATERIALS ANDMETHODS:
We conducted a retrospective study of blood isolates of B. cepacia taken at our hospital between January 2004 and December 2014. Patient clinical data were obtained by retrospective review of electronic medical records. We constructed a dendrogram for B. cepacia isolates from two children and five adult patients.RESULTS:
A total of 14 pediatric patients and 69 adult patients were identified as having B. cepacia bacteremia. In 2014, higher rates of B. cepacia bacteremia were observed in children. Most of them required Intensive Care Unit (ICU) care (12/14). In eleven children, sputum cultures were examined, and five of these children had the same strain of B. cepacia that grew out from their blood samples. Antibiotics were administered based on antibiotic sensitivity results. Four children expired despite treatment. Compared to children, there were no demonstrative differences in adults, except for history of ICU care.CONCLUSION:
Although there were not many pediatric cases at our hospital, awareness of colonization through hospital-acquired infection and effective therapy for infection of B. cepacia is needed, as it can cause mortality and morbidity.
Full text:
Available
Health context:
Sustainable Health Agenda for the Americas
Health problem:
Goal 6: Information systems for health
Database:
WPRIM (Western Pacific)
Main subject:
Microbial Sensitivity Tests
/
Cross Infection
/
Incidence
/
Disease Outbreaks
/
Retrospective Studies
/
Treatment Outcome
/
Burkholderia cepacia
/
Bacteremia
/
Burkholderia Infections
/
Republic of Korea
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Aged, 80 and over
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Yonsei Medical Journal
Year:
2016
Document type:
Article