Fracture Incidence and Risk of Osteoporosis in Female Type 2 Diabetic Patients in Korea
Diabetes & Metabolism Journal
; : 144-150, 2012.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-186630
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
There are no published data regarding fracture risk in type 2 diabetic patients in Korea. In this study, we compared the fracture incidence and risk of osteoporosis of type 2 diabetic female patients with those in a non-diabetic hypertensive cohort.METHODS:
The incidence of fracture in a type 2 diabetic cohort was compared with that in a non-diabetic hypertensive cohort over the course of 7 years. Female type 2 diabetic and non-diabetic hypertensive patients who visited Eulji General Hospital outpatient clinic from January 2004 to April 2004 were assigned to the diabetic cohort and the non-diabetic hypertensive cohort, respectively. Surveys on fracture event, use of anti-osteoporosis medications, and bone mineral density were performed.RESULTS:
The number of fractures was 88 in the female diabetic cohort (n=1,268, 60.6+/-11.5 years) and 57 in the female non-diabetic hypertensive cohort (n=1,014, 61.4+/-11.7 years). The RR in the diabetic cohort was 1.38 (P=0.064; 95% confidence interval [CI], 0.98 to 1.94) when adjusted for age. Diabetic patients with microvascular complications (61.0%) showed a higher RR of 1.81 (P=0.014; 95% CI, 1.13 to 2.92) compared with those without these complications. The prevalence of osteoporosis was comparable between the groups, while use of anti-osteoporosis medication was more common in the diabetic cohort (12.8%) than in the hypertensive cohort (4.5%) (P<0.001).CONCLUSION:
In our study, a higher fracture risk was observed in female type 2 diabetics with microvascular complications. Special concern for this risk group is warranted.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Osteoporosis
/
Bone Density
/
Incidence
/
Prevalence
/
Cohort Studies
/
Diabetes Mellitus, Type 2
/
Ambulatory Care Facilities
/
Hospitals, General
/
Korea
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Diabetes & Metabolism Journal
Year:
2012
Document type:
Article