Expression of E-cadherin according to the Presence of High Risk Prognostic Factors, Clinical Stages and Pathologic Types in Cervical Cancer Patients Treated by Radical Hysterectomy / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
; : 974-979, 2000.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-187009
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To analyze the relationship between the degree of expression of E-cadherin and presence of high risk prognostic factors (lymph node metastasis or parametrium involvement), clinical stages and pathologic types in invasive cervical cancer.METHODS:
An immunohistochemical technique has been applied to formalin-fixed, paraffin- embedded samples from 20 radical hysterectomy without risk factors and 16 radical hysterectomy with risk factors. The degree of expressions of E-cadherin immunostaining was compared with the International Federation of Gynecology and Obstetrics (FIGO) stage, presence of high risk prognostic factors, and pathologic types.RESULTS:
The difference of the degree of expression of E-cadherin was not statistically significant between high-risk group (lymph node metastasis or parametrium invasion) and non-risk group. The difference of the degree of expression of E-cadherin was not statistically significant according to clinical stages and variable pathologic types either.CONCLUSIONS:
These results suggest that the degree of the expression of E-cadherin has no relationship with known high risk prognostic factors, clinical stages and pathologic types in invasive cervical cancer.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Cadherins
/
Uterine Cervical Neoplasms
/
Risk Factors
/
Gynecology
/
Hysterectomy
/
Neoplasm Metastasis
/
Obstetrics
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2000
Document type:
Article