A Case of Acute Necrotizing Encephalopathy
Journal of the Korean Pediatric Society
; : 954-958, 2001.
Article
in Ko
| WPRIM
| ID: wpr-19142
Responsible library:
WPRO
ABSTRACT
This disease predominantly affects infants and young children living in Japan and Taiwan, and manifests itself as acute encephalopathy following viral infections. The hallmark of this encephalopathy is multifocal, symmetric brain lesions affecting bilateral thalamus, brainstem tegmentum, cerebral periventricular white matter and cerebellar medulla, which can be visualized by computed tomography and magnetic resonance imaging. Both the gray and white matter are involved, with neuropathological evidence of local breakdown of the blood-brain barrier. The prognosis was poor in the 1980s, but has improved recently. A characteristic combination of focal neurologic signs is often recognized as the sequelae. We experienced a case of a 7-month-old male infant who had been transferred to our hospital for comatous mentality and clonic seizure of both arms and legs. We report this case with a review of the related literatures.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Arm
/
Prognosis
/
Seizures
/
Taiwan
/
Thalamus
/
Brain
/
Brain Stem
/
Magnetic Resonance Imaging
/
Blood-Brain Barrier
/
Japan
Type of study:
Prognostic_studies
Limits:
Child
/
Humans
/
Infant
/
Male
Country/Region as subject:
Asia
Language:
Ko
Journal:
Journal of the Korean Pediatric Society
Year:
2001
Document type:
Article