An Autopsy Case of Pick's Disease
Journal of the Korean Neurological Association
; : 786-789, 2000.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-193153
Responsible library:
WPRO
ABSTRACT
Pick's disease is a rare neurodegenerative disorder presenting cortical type of dementia. Pick's disease shows unique clinical and pathological features, that are due to a degeneration of fronto-temporal lobes of the cerebrum. The authors experienced a case of Pick's disease in a 58-year-old male patient who had dementia symptoms for five years. The patient showed compulsive behavior since five years ago. Memory decline started from four years ago and progressed. Brain CT disclosed lobar atrophy of the cerebral gyri in frontal and temporal lobes. He died of septicemia associated with aspiration pneumonia. At autopsy, both cerebral hemispheres showed marked encephalomalacia. The gyral atrophy was moderately severe in prefrontal and anterior temporal lobes. Coronal section disclosed moderate dilatation of the lateral ventricles. Microscopically, there were marked neuronal loss in prefrontal and anterior temporal cortices. Also noted were Pick's cells and Pick's body in occasional pyramidal cells preserved.
Full text:
Available
Health context:
SDG3 - Target 3.3 End transmission of communicable diseases
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Pneumonia
/
Sepsis
/
Alzheimer’s Disease and other Dementias
/
Mental Health and Behavioral Disorders
/
Other Respiratory Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Pneumonia, Aspiration
/
Atrophy
/
Autopsy
/
Temporal Lobe
/
Brain
/
Pyramidal Cells
/
Sepsis
/
Compulsive Behavior
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Neurodegenerative Diseases
/
Lateral Ventricles
Limits:
Humans
/
Male
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
2000
Document type:
Article