A Patient with RhD(el) (1227G>A) Failed to Produce Detectable Anti-D after Transfusion of RhD Positive Red Blood Cells / 대한수혈학회지
Korean Journal of Blood Transfusion
; : 153-158, 2006.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-197057
Responsible library:
WPRO
ABSTRACT
Only 0.15% of all donors in Korea are RhD negative, which has led to a chronic shortage of RhD negative blood. Most physicians are aware of the potential for RhD alloimmunization after transfusing RhD+ red blood cells into RhD- patients. Hence, the undertransfusion of RhD- patients might be occurring in Korea. A 66-year-old man without a history of transfusion tested negative for anti-D in his serum. In an emergency situation where RhD- blood was unavailable, the patient received two units of RhD+ RBCs. Anti-D was not detected over three months after the transfusion. The red cells of the patient showed no agglutination with the anti-D reagent and a negative result by the standard weak D test. The polymerase chain reaction-sequence specific primers (PCR-SSP) and sequencing revealed D(el) (1227G>A) in the patient.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Tissue Donors
/
Agglutination
/
Emergencies
/
Erythrocytes
/
Korea
Limits:
Aged
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Blood Transfusion
Year:
2006
Document type:
Article