Gamma Knife Radiosurgery for Remnant or Recurred Craniopharyngiomas
Journal of Korean Neurosurgical Society
; : 96-101, 2006.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-198033
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
The authors assess the long term effectiveness of gamma knife radiosurgery(GKS) for remnant or recurred craniopharyngiomas on tumor control and possibly set proper radiation dose for tumor control with utmost preservation of the adjacent structures.METHODS:
Sixteen GKS were done in 14 patients with recurred or remnant craniopharyngiomas after surgery. Mean follow up duration was 44.2 months (range 11.3~123.6 months). Follow up MR imagings were analyzed.RESULTS:
Mean tumor volume was 3.6 cm3 (range 0.6~18 cm3) and mean margin dose was 12.2Gy (range 8~22.4Gy). Tumor control was achieved in 87.5% (14 of 16 tumors) which were either solid or cystic in nature. Dose to optic apparatus was mean 7.9Gy and no radiation related complications were observed.CONCLUSION:
GKS seems to be effective treatment modality for craniopharyngiomas regardless of nature of tumor whether it is cystic or solid. Dose of 8 to 8.5Gy may be sufficient to achieve long term tumor control for remnant or recurred craniopharyngiomas.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Follow-Up Studies
/
Radiosurgery
/
Craniopharyngioma
/
Tumor Burden
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Journal of Korean Neurosurgical Society
Year:
2006
Document type:
Article