A case of pineal germioma presenting with diabetes insipidus / 대한내과학회지
Korean Journal of Medicine
; : 305-309, 2000.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-198354
Responsible library:
WPRO
ABSTRACT
Central diabetes insipidus caused by pineal gland neoplasm is rare. Here, we describe a case of central diabetes insipidus and pineal germinoma with seeding to pituitary stalk along CSF pathway. A 27 year-old male patient was admitted due to polyuria, polydipsia, headache, vomiting, diplopia, and decreased visual acuity for recent two months. Urine osmolality measured after water deprivation was below 100mOsm/kg. However, urine osmolality increasd above 300 mOsm/kg with pitressin administration. Brain MRI showed a 2cm sized mass with seeding into pituitary stalk along CSF in pineal region. Surgical biopsy revealed pineal germinoma. Two cycles of chemotherapy with etoposide and cis-platin were done followed by brain irradiation(2,500cGy). Follow up brain MRI after second chemotherapy showed complete remission. The patient had no neurologic and endocrinologic deficit after the treatment.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Osmolar Concentration
/
Pineal Gland
/
Pinealoma
/
Pituitary Gland
/
Polyuria
/
Vomiting
/
Water Deprivation
/
Biopsy
/
Brain
/
Vasopressins
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2000
Document type:
Article