Performance of a low cost magnifying device, magnivisualizer, versus colposcope for detection of pre-cancer and cancerous lesions of uterine cervix / 부인종양
Journal of Gynecologic Oncology
; : 282-286, 2014.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-202143
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To assess the performance of a low cost magnifying device (Magnivisualizer) compared to a standard optical colposcope for detection of precancerous and cancerous lesions of the uterine cervix.METHODS:
A total of 659 consecutive symptomatic women attending a gynecologic outpatient clinic underwent unaided visual inspection followed by cytology, visual inspection of the cervix using 5% acetic acid (VIA), and VIA under magnification (VIAM) with the Magnivisualizer. All women, independently of test results, were referred for colposcopic examination. Colposcopic-directed biopsies were obtained from all positive lesions and compared to positive VIAM cases.RESULTS:
The detection rate for VIA positive lesions was 12% (134/659), while it was 29% for VIAM positive lesions (191/659). The sensitivities of detection of cervical intraepithelial neoplasia (CIN) 2 and higher lesions were 61.7% for VIA, 88.3% for VIAM, and 86.7% for colposcopy, with a specificity of 58.5% for VIA, 55.8% for VIAM, and 90.4% for colposcopy. The performance of colposcopy and VIAM was moderate (kappa, 0.48; 95% confidence interval [CI], 0.41 to 0.54) for detection of CIN 1 and higher lesions and excellent (kappa, 0.87; 95% CI, 0.82 to 0.94) for detection of CIN 2 and higher lesions.CONCLUSION:
In low resource settings, where colposcopic facilities are not available at the community level, a simple low-cost, handheld Magnivisualizer can be considered a valid option for detection of cervical precancerous and cancerous lesions. However, it cannot replace traditional colposcopy because it has a low specificity that results in many unnecessary biopsies.
Full text:
Available
Health context:
Sustainable Health Agenda for the Americas
Health problem:
Goal 4: Health financing
Database:
WPRIM (Western Pacific)
Main subject:
Outpatient Clinics, Hospital
/
Biopsy
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Uterine Cervical Dysplasia
/
Uterine Cervical Neoplasms
/
Reproducibility of Results
/
Colposcopy
/
Acetic Acid
/
Colposcopes
/
Equipment Design
/
Early Detection of Cancer
Type of study:
Diagnostic study
/
Health economic evaluation
/
Screening study
Limits:
Adult
/
Aged
/
Female
/
Humans
Language:
English
Journal:
Journal of Gynecologic Oncology
Year:
2014
Document type:
Article