Epidemiological Investigation of Yersinia pseudotuberculosis Infection in Korean / 대한임상병리학회지
Korean Journal of Clinical Pathology
; : 1068-1075, 1997.
Article
in Ko
| WPRIM
| ID: wpr-204947
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
The purpose of this study is to prove that human infection of Yersinia pseudotuberculosis might be occurred by drinking of mountain spring water contaminated with wild mice excreta through epidemiological tool.METHOD:
Y. pseudotuberculosis strains which were isolated from patient stools, mountain spring water and mice excreta were analysed by serotyping of O antigen and plasmid DNA profile (Restriction Endonuclease Analysis of Plasmic DNA analysis REAP) assay Also reservoir rate of Y. pseudotuberculosis was calculated from wild mice which were captured throughout Korean mountains.RESULTS:
Reservoir rate of Y. pseudotuberculosis from wild mice in Korea was 0.85% and was not higher than that in other country. The analysis of 66 strains of Y. pseudotuberculosis showed that 36 strains of serotype 15, REAP B type, 24 strains of serotype 4b, REAP D type, and 1 strain of serotype 4b, REAP new unclassifiable type, but 5 strains didn't have plasmic (serotype 153, 112) .Especially same 4b, D type of Y. pseudotuberculosis was isolated from patient stools, mountain spring water and wild mouse (Apodemus agrarius) excretion and this fact was considered that Y. pseudotuberculosis strains from 3 groups were closely correlated epidemiologically. Also serotype 15, REAP B strains were isolated from patient stools and mountain spring water, but were not isolated from wild mice yet and 15, B type was isolated from Korea only and considered as native Korean strain which had not isolated in other countries yet.CONCLUSIONS:
Human Y. pseudotuberculosis infection in Korea was occurred by drinking of contaminated mountain spring water and A. agrarius was one of main reservoir which contaminates mountain spring waters in Korea, Also above antigenic distribution of Y. pseudotuberculosis would be useful for development of ELISA kit of Korean type.
Full text:
1
Database:
WPRIM
Main subject:
Plasmids
/
Yersinia
/
Yersinia pseudotuberculosis
/
DNA
/
Enzyme-Linked Immunosorbent Assay
/
Serotyping
/
O Antigens
/
Drinking
/
Korea
Limits:
Animals
/
Humans
Country/Region as subject:
Asia
Language:
Ko
Journal:
Korean Journal of Clinical Pathology
Year:
1997
Document type:
Article