Craniopharyngioma: Comparison of Tumor Characteristics Relevant with Initial Symptomatology between Children and Adults
Journal of Korean Neurosurgical Society
; : 985-991, 2001.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-208544
Responsible library:
WPRO
ABSTRACT
OBJECTIVES:
The craniopharyngioma is a benign tumor located at least in part in the suprasellar cistern. However, the symptoms and signs from this tumor may be determined not only by the location of the tumor but also by its size and the age of the patient. The objective of our study is to analyze retrospectively the clinical manifestations of craniopharyngiomas with regards to tumor characteristics in children and adults. MATERIALS ANDMETHODS:
Twenty-three patients(16 adults, 7 children) treated for craniopharyngioma between 1990 and 1999 were studied to demonstrate the relationship of tumor size, growth pattern, and its invasiveness with clinical symptoms. As part of the assessment, 16 adults(MF=88, mean age43.7 years) and 7 children(MF=52, mean age10.1 years) underwent magnetic resonance(MR) imaging and computerized tomography(CT) scanning with a three-dimensional volume acquisition sequence.RESULTS:
The three major cardinal signs were defined to increased intracranial pressure, endocrine dysfunction, and visual problems. The tumor size in child group was larger than that in adult group. Also, visual problems, symptoms of increased intracranial pressure and hydrocephalus were more frequently observed in child group. However, endocrine dysfunction and neuropsychological symptoms related with hypothalamic connections to the thalamus, pituitary, frontal lobe, and other cortical areas were more frequent in adult group.Conclusions:
In our series, the tumor size and invasiveness of craniopharyngioma revealed to be relevent with initial symptoms of increased intracranial pressure and visual symptoms which were more frequent in child group. As for the growth pattern, we did not find major difference between adults and children.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Thalamus
/
Intracranial Pressure
/
Retrospective Studies
/
Craniopharyngioma
/
Frontal Lobe
/
Hydrocephalus
Type of study:
Diagnostic study
/
Observational study
Limits:
Adult
/
Child
/
Humans
Language:
Korean
Journal:
Journal of Korean Neurosurgical Society
Year:
2001
Document type:
Article