Characteristics and Detection Rate of Thyroidal Incidentaloma using ¹⁸F-FDG PET-CT / 대한내분비외과학회지
Korean Journal of Endocrine Surgery
; : 38-42, 2008.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-210418
Responsible library:
WPRO
ABSTRACT
PURPOSE:
PET-CT is often used to differentiate benign or malignant thyroid incidentalomas. In this retrospective study, we evaluated whether the ¹⁸F-FDG uptake pattern and PET-CT findings improved accuracy over the standardized uptake value (SUV).METHODS:
¹⁸F-FDG PET-CT was performed on 2,178 subjects from August, 2004, to October, 2007, in Sung-ae Hospital. PET-CT was performed on 806 patients (37%) with suspected or known nonthyroidal cancer and 1,372 healthy subjects (63%) without a previous history of cancer. We investigated the clinical characteristics of patients, history, standardized uptake value (SUV), ultrasonography, and hormone levels in blood. Thyroidal cancer was confirmed by ultrasonography-guided fine needle aspiration and pathology after thyroid operation.RESULTS:
The prevalence of focal thyroid lesions on PET-CT was 8.8% (191/2178). Thyroid cancer confirmation was 7.9% (15/191). The maximum SUV of malignant thyroid lesions were significantly higher than that of benign lesions (7.00±3.08 vs. 4.49±1.84, P<0.001).CONCLUSION:
PET-CT image interpretation that includes 18F-FDG uptake and SUV is better than PET-CT alone for differentiating benign and malignant lesions. Thyroid cancer risk increases as SUVmax levels increase.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Thyroid Gland
/
Thyroid Neoplasms
/
Prevalence
/
Retrospective Studies
/
Ultrasonography
/
Fluorodeoxyglucose F18
/
Biopsy, Fine-Needle
/
Healthy Volunteers
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Endocrine Surgery
Year:
2008
Document type:
Article