The Effect of Sevoflurane Anesthesia on the Phase Relationship between Systolic Blood Pressure and Heart Rate / 대한마취과학회지
Korean Journal of Anesthesiology
; : 571-576, 2007.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-218881
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
The phase relationship indicates the time delay between the input signal (systolic blood pressure, SBP) and output signal (R-R interval, RRI). In contrast to the awake state, little is known about the effects of general anesthesia on the phase shift. In the present study, we tested the hypothesis that sevoflurane anesthesia causes a phase change between the two signals.METHODS:
We assessed changes in phase, coherence, and baroreflex sensitivity between SBP and RRI by the use of transfer function analysis in 50 ASA 1 patients during the awake state and during end-tidal 2% sevoflurane-50% N2O anesthesia.RESULTS:
SBP and RRI decreased significantly during sevoflurane anesthesia (P < 0.001). The phase in the low frequency (LF) region remained unchanged, but the phase in the high frequency (HF) region changed significantly from -29.52 +/- 50.70 to 27.28 +/- 80.22 degrees during sevoflurane anesthesia (P < 0.001). Coherence and baroreflex sensitivity between the two signals in the LF and HF regions decreased significantly during sevoflurane anesthesia (P < 0.001, respectively).CONCLUSIONS:
We found that in the HF region and not in the LF region, sevoflurane anesthesia provokes the shift of the SBP-RRI phase relationship, suggesting that this change is inconsistent with a vagally mediated response.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Blood Pressure
/
Baroreflex
/
Heart
/
Heart Rate
/
Anesthesia
/
Anesthesia, General
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2007
Document type:
Article