A Case of Acute Generalized Exanthematous Pustulosis Induced by Hydroxychloroquine / 대한피부과학회지
Korean Journal of Dermatology
; : 138-140, 2008.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-228407
Responsible library:
WPRO
ABSTRACT
Hydroxychloroquine, an 4-amino-quinoline, has been used widely for the treatment of lupus erythematosus due to its anti-inflammatory and immuno-modulatory activities, as well as for the treatment of malaria. A 37-year-old woman who was suspected as lupus erythematosus and treated with hydroxychloroquine for 3 weeks was seen with exfoliated annular patches and pustules on the trunk, neck, and extremities. Histological examination showed subcorneal and spongiform neutrophilic pustules with perivascular lymphocytes, eosinophils and neutrophils infiltrations. The patient had been treated with systemic steroid and antihistamine. The pustular lesions had improved 2 weeks later without recurrence. The causative drug was confirmed by a positive patch test.
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Malaria
/
Neglected Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Patch Tests
/
Lymphocytes
/
Eosinophils
/
Extremities
/
Acute Generalized Exanthematous Pustulosis
/
Hydroxychloroquine
/
Malaria
/
Neck
/
Neutrophils
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2008
Document type:
Article