Optimal sedative dose of propofol to start MRI in children with cerebral palsy / 대한마취과학회지
Korean Journal of Anesthesiology
; : 216-219, 2011.
Article
in En
| WPRIM
| ID: wpr-229279
Responsible library:
WPRO
ABSTRACT
BACKGROUND: This study was designed to determine the optimal sedative dose of propofol to start brain magnetic resonance imaging (MRI) in children with cerebral palsy (CP). METHODS: Twenty children, aged 0.5-5 years, were administered propofol to achieve a University of Michigan Sedation Scale (UMSS) score > or = 3 in the MRI room. The proper dose of propofol was determined using the up-and-down method. RESULTS: The ED50 and ED95 for successful sedation with a UMSS > or = 3 were 2.07 mg/kg (95% CI 1.69-2.56) and 2.69 mg/kg (95% CI 2.35-5.59). Respiratory events occurred in 5 patients and were resolved with neck extension, chin lift, or transient respiratory assistance with successful sedation. CONCLUSIONS: Low dose propofol can safely facilitate the initiation of MRI in children with CP.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Brain
/
Magnetic Resonance Imaging
/
Propofol
/
Cerebral Palsy
/
Michigan
/
Chin
/
Neck
Limits:
Aged
/
Child
/
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Korean Journal of Anesthesiology
Year:
2011
Document type:
Article