Value of fractional nitric oxide concentration in exhaled breath in assessing level of asthma control in children / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 29-32, 2013.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-236881
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the value of fractional nitric oxide concentration in exhaled breath (FeNO) in assessing the level of asthma control in children.</p><p><b>METHODS</b>A total of 226 asthmatic children were divided into controlled asthma (n= 86), partially controlled asthma (n=63), and uncontrolled asthma groups (n=77). Ninety healthy children were enrolled as controls. FeNO was measured for both asthmatic and healthy children using the Swedish-designed NIOX system.</p><p><b>RESULTS</b>The control group had an FeNO of 14±6 ppb, the controlled asthma group had an FeNO of 29±26 ppb, the partially controlled asthma group had an FeNO of 32±30 ppb, and the uncontrolled asthma group had an FeNO of 40±32 ppb. The three asthma groups showed significantly higher FeNO than the control group (P<0.05). The uncontrolled asthma group showed significantly higher FeNO than the controlled asthma group (P<0.05), but there were no significant differences in FeNO between the partially controlled and uncontrolled asthma groups and between the partially controlled and controlled asthma groups (P>0.05).</p><p><b>CONCLUSIONS</b>Asthmatic children have significantly higher FeNO than healthy children, and FeNO is correlated with the level of asthma control.</p>
Full text:
Available
Health context:
Sustainable Health Agenda for the Americas
/
SDG3 - Health and Well-Being
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Goal 9: Noncommunicable diseases and mental health
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Target 3.4: Reduce premature mortality due to noncommunicable diseases
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Target 3.2: Reduce avoidable death in newborns and children under 5
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Asthma
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Other Respiratory Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Asthma
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Therapeutics
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Breath Tests
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Forced Expiratory Volume
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Diagnosis
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Nitric Oxide
Type of study:
Diagnostic study
Limits:
Adolescent
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Child
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Female
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Humans
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Male
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2013
Document type:
Article