Six-month clinical outcomes of Firebird 2TM sirolimus-eluting stent implantation in real-world patients with coronary artery diseases / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 831-835, 2011.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-239939
Responsible library:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>The Firebird 2(TM) sirolimus-eluting stent (Firebird 2 stent) is a second-generation sirolimus-eluting stent which has a cobalt-chromium alloy stent platform, a brand new bracket structure, and two layers of styrene-butylenes-styrene polymer coatings with better biocompatibility. The Firebird 2(TM) cObalt-Chromium alloy sirolimus-elUting Stent registry (FOCUS registry) aimed to evaluate the safety and efficacy of the Firebird 2 stent in patients with coronary artery disease in daily practice.</p><p><b>METHODS</b>The FOCUS registry is a prospective, non-randomized, international multi-center, single-arm clinical registry. Between March 2009 and February 2010, 5084 patients receiving at least 1 Firebird 2 stent during daily clinical practice at 83 medical centers were enrolled.</p><p><b>RESULTS</b>Of the 5084 patients enrolled in the registry, 5077 and 5058 were respectively available for 30 days and 6 months follow-up. The 30-day rate of major adverse cardiac events (MACE) was 1.20%, including 13 cardiac deaths, 46 non-fatal myocardial infarction (MI), and 6 target vessel revascularization (TVR). At 6 months follow-up, the rate of MACE was 1.80%. There were 32 cardiac deaths, 48 non-fatal MI, and 15 TVR. According to the Academic Research Consortium definition, definite/probable stent thrombosis (ST) occurred in 0.43% (22/5058) of patients, including 8 cases of acute ST, 11 subacute ST, and 3 late ST.</p><p><b>CONCLUSION</b>The Firebird 2 stent showed the promising efficacy and safety at 30 days and 6 months in a real-world population of patients with coronary artery diseases.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Coronary Artery Disease
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Angioplasty, Balloon, Coronary
/
Prospective Studies
/
Treatment Outcome
/
Sirolimus
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Therapeutic Uses
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Drug-Eluting Stents
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Methods
Type of study:
Controlled clinical trial
/
Observational study
Limits:
Adult
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Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Chinese Medical Journal
Year:
2011
Document type:
Article