Palliative local radiotherapy in the treatment of tumor-stage cutaneous T-cell lymphoma/mycosis fungoides / 中国医学科学杂志(英文版)
Chinese Medical Sciences Journal
; (4): 33-37, 2014.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-242904
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To determine the efficacy of palliative radiotherapy in treating tumor-stage cutaneous T-cell lymphoma/mycosis fungoides (MF).</p><p><b>METHODS</b>From January 2008 to January 2013, a total of 11 patients with tumor-stage MF were treated with local radiation therapy in Peking Union Medical College Hospital. The median age of these patients was 53.36 ± 14.45 years. Female-male ratio was 11.2. The average course of disease was 10.82 ± 3.37 years. All the patients were treated with local electronic beam irradiation with a total median dosage of 48.55 ± 9.51 (40-74) Gy in an average of 24.55 ± 5.57 (20-40) fractions, 5 fractions per week.</p><p><b>RESULTS</b>The median follow-up time was 55.27 ± 29.3 (13-103) months. No severe acute or chronic side effects of irradiation were observed. Complete clinical response (CR) rate of the radiated sites was 54.5% (6/11), partial response (PR) rate was 36.4% (4/11), and the overall response rate (CR+PR) was 90.9%. One patient showed no response.</p><p><b>CONCLUSION</b>Local radiotherapy with psolaren plus ultraviolet A and/or interferon maintaining treatment is an effective palliative therapy in the treatment of tumor-stage MF patients.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Palliative Care
/
Pathology
/
PUVA Therapy
/
Radiotherapy
/
Radiotherapy Dosage
/
Skin Neoplasms
/
Lymphoma, T-Cell, Cutaneous
/
Mycosis Fungoides
/
Interferons
/
Treatment Outcome
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Chinese Medical Sciences Journal
Year:
2014
Document type:
Article