Photodynamic therapy of condyloma acuminata in pregnant women / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 2925-2928, 2012.
Article
in En
| WPRIM
| ID: wpr-244324
Responsible library:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>Photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA) is an emerging technique for the treatment of genital human papillomavirus (HPV)-induced benign and premalignant lesions. We report here in a case series of condyloma acuminata (CA) in pregnancy successfully treated with ALA-PDT.</p><p><b>METHODS</b>Five pregnant patients with CA received three to four times treatment respectively. Patients were followed up for 6 - 23 months after treatment.</p><p><b>RESULTS</b>The clearance rate of genital warts was 100%. No recurrence was found during the follow-up period. Major adverse events reported were mild erosion, pain, and local edema. All pregnancies resulted in healthy live births without delivery complications.</p><p><b>CONCLUSIONS</b>PDT with topical ALA seems to be safe and effective in the treatment of CA in pregnancy. It demonstrated high clearance rate of warts, was well-tolerated by patients, and showed no adverse effects on mothers or fetuses. ALA-PDT may be an ideal strategy of treatment for pregnant women with CA.</p>
Full text:
1
Database:
WPRIM
Main subject:
Photochemotherapy
/
Condylomata Acuminata
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Therapeutic Uses
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Drug Therapy
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Aminolevulinic Acid
/
Methods
Limits:
Adult
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Female
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Humans
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Pregnancy
Language:
En
Journal:
Chinese Medical Journal
Year:
2012
Document type:
Article