Preparation of inclusion complex of daidzein and hydropropyl-beta-cyclodextrin / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2039-2041, 2006.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-246026
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To prepare an inclusion complex of daidzein and hydropropyl-beta-cyclodextrin to enhance the solubility of daidzein.</p><p><b>METHOD</b>The inclusion complex of daidzein was prepared by the solution stirring method. The binary system of daidzein and HP-beta-CD was confirmed by differential thermal, thermogravimetry analysis, infrared spectroscopy and X-ray diffractometry.</p><p><b>RESULT</b>The drug content in the inclusion complex was 6. 76% and the solubility was 13.68 mg x mL(-1). The identification results showed that the inclusion complex was formed.</p><p><b>CONCLUSION</b>The preparation method of the inclusion complex of daidzein and hydropropyl-beta-cyclodextrin is simple and available, with a increased solubility of daidzein.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Solubility
/
X-Ray Diffraction
/
Chemistry
/
Spectroscopy, Fourier Transform Infrared
/
Beta-Cyclodextrins
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Differential Thermal Analysis
/
Drug Compounding
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2-Hydroxypropyl-beta-cyclodextrin
/
Isoflavones
/
Methods
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2006
Document type:
Article
