Effects of Kang Gang Qian Granule (KGQG) on clinical and pathological features in chronic hepatitis B patients / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 369-371, 2007.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-248750
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the efficacy of KGQG and its therapeutic mechanisms in chronic hepatitis B patients with liver fibrosis.</p><p><b>METHODS</b>57 chronic hepatitis B patients with liver fibrosis were randomly divided into two groups 45 cases in KGQG group were treated by KGQG and routine medications; 12 cases in control group were treated by routine medications only. Serum liver function test results, PCIII, CIV, HA and liver biopsy results of these 57 patients were simultaneously collected and analyzed before and after this intervention.</p><p><b>RESULTS</b>KGQG group showed better efficacy over control group in liver function recovery, decrease of serum PCIII, CIV, HA levels and liver pathologic grades (P 0.05 or 0.01).</p><p><b>CONCLUSION</b>The KGQG could effectively ameliorate liver function and facilitate the inhibition and degradation of liver fibrosis in chronic hepatitis B patients, which may be developed as a novel therapeusis to treat this hard-to-cure disease.</p>
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Drugs, Chinese Herbal
/
Immunohistochemistry
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Hepatitis B, Chronic
/
Collagen Type IV
/
Therapeutic Uses
/
Drug Therapy
/
Liver Cirrhosis
/
Medicine, Chinese Traditional
Type of study:
Diagnostic study
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2007
Document type:
Article