Progress in the study of near-infrared fluorescent probes for the detection of β-amyloid deposition in Alzheimer's disease / 药学学报
Acta Pharmaceutica Sinica
; (12): 528-534, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-251746
Responsible library:
WPRO
ABSTRACT
Alzheimer's disease (AD) is the most common cause of cognitive impairment in older people. With the aging of society is more and more serious, AD caused great burden to patients and society. A β is a classical biomarker of AD, which has been widely used in clinical diagnosis of AD patients. Compared with positron emission tomography (PET) and single photon emission computed tomography (SPECT), near infrared fluorescence imaging has many advantages including highly sensitive, non-invasive, safety and inexpensive. Therefore, many research groups have focused on developing the molecular probes of near-infrared fluorescence (NIRF) imaging. In this article, we will review the progress of the probes of NIRF.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Molecular Probes
/
Tomography, Emission-Computed, Single-Photon
/
Amyloid beta-Peptides
/
Spectroscopy, Near-Infrared
/
Positron-Emission Tomography
/
Diagnosis
/
Alzheimer Disease
/
Fluorescence
/
Fluorescent Dyes
Type of study:
Diagnostic study
Limits:
Humans
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2015
Document type:
Article