Computational prediction of microRNA genes in silkworm genome / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Journal of Zhejiang University. Science. B
; (12): 806-816, 2006.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-251851
Responsible library:
WPRO
ABSTRACT
MicroRNAs (miRNAs) constitute a novel, extensive class of small RNAs (approximately 21 nucleotides), and play important gene-regulation roles during growth and development in various organisms. Here we conducted a homology search to identify homologs of previously validated miRNAs from silkworm genome. We identified 24 potential miRNA genes, and gave each of them a name according to the common criteria. Interestingly, we found that a great number of newly identified miRNAs were conserved in silkworm and Drosophila, and family alignment revealed that miRNA families might possess single nucleotide polymorphisms. miRNA gene clusters and possible functions of complement miRNA pairs are discussed.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Bombyx
/
Thermodynamics
/
Software
/
Molecular Sequence Data
/
Base Sequence
/
Sequence Homology, Nucleic Acid
/
Cluster Analysis
/
Multigene Family
/
Genome
/
Computational Biology
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Journal of Zhejiang University. Science. B
Year:
2006
Document type:
Article