Relationship between placental pathology and small-for-gestational age neonates / 中华病理学杂志
Chinese Journal of Pathology
; (12): 737-741, 2012.
Article
in Zh
| WPRIM
| ID: wpr-256303
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between pathological abnormalities of placenta and small-for-gestational-age neonates.</p><p><b>METHODS</b>One hundred placentas of small-for-gestational-age (SGA group) and 200 appropriate-for-gestational-age (AGA group) with single living birth in third trimester were investigated by gross and microscopic examination. The AGA placentas were collected from 2 cases following every SGA placenta. All cases were collected from Shanghai Changning District Maternity and Infant Health Hospital from January 2010 to December 2011.</p><p><b>RESULTS</b>The gestational week, neonatal birth weight, full-term neonatal birth weight, the preterm birth rate and vaginal spontaneous delivery rate were significantly lower in SGA group than that in AGA group (P < 0.002). Full-term placental volume, placental weight and fetal placental weight ratio were lower in SGA group than that in AGA group (P < 0.05). Unusual insertion and torsion of umbilical cord were more common in SGA group (P < 0.05). Syncytial knots increase, avascular villi and villous infarcts were significantly higher in SGA group (P < 0.005), but there were no significant difference between SGA group and AGA group in intervillous thrombi, chronic villitis and chorangiosis (P > 0.05). Gestational hypertension disease and abnormality of fetal monitoring were more common in SGA group (P < 0.05).</p><p><b>CONCLUSIONS</b>Gestational hypertension disease is the main clinical cause of SGA. Some placental abnormality can affect the growth and development of intrauterine fetus.</p>
Full text:
1
Database:
WPRIM
Main subject:
Pathology
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Placenta
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Umbilical Cord
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Birth Weight
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Infant, Small for Gestational Age
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Gestational Age
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Hypertension, Pregnancy-Induced
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Torsion, Mechanical
Limits:
Female
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Humans
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Newborn
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Pregnancy
Language:
Zh
Journal:
Chinese Journal of Pathology
Year:
2012
Document type:
Article