Erdi Biejia decoction for erectile dysfunction with kidney-yin deficiency / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the clinical efficacy of the Chinese medicine Erdi Biejia Decoction in the treatment of erectile dysfunction (ED) with kidney-yin deficiency, and explore its action mechanism and the nourishing yin doctrine in the treatment of ED.</p><p><b>METHODS</b>We equally randomized 60 ED patients with kidney-yin deficiency into a treatment and a control group, the former treated with oral Erdi Biejia Decoction, and the latter given placebo, for a course of 8 weeks. We compared the IIEF scores and levels of sex hormones T, E2, LH, FSH and PRL between the two groups before and after treatment.</p><p><b>RESULTS</b>Compared with the control group, the treatment group showed a significantly higher total effectiveness rate (36.67% vs 63.33%, P < 0.05), IIEF score (18.19 +/- 5.20 vs 23.08 +/-4.71, P < 0.05) and plasma T level (116.41 +/- 3.19 vs 20.14 +/- 2.99, P < 0.05), but remarkably lower levels of E2, LH, FSH and PRL (P < 0.05) after medication, all with statistically significant differences from pre-medication (P < 0.05).</p><p><b>CONCLUSION</b>Erdi Biejia Decoction is efficacious in the treatment of ED with kidney-yin deficiency, with no obvious adverse effects.</p>