Correlation between Plasma Level of Monocyte Chemotactic Protein 1 and Acute Aortic Dissection / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the potential association between monocyte chemotactic protein 1(MCP-1)in plasma and acute aortic dissection(AAD).</p><p><b>METHODS</b>A total of 110 patients with Stanford type A AAD who had received emergent surgical treatment in Xiangya hospital from September 2011 to September 2014 were enrolled in as the study group;meanwhile,110 patients with simple hypertension who had received treatment in department of cardiology were chosen as the control group. The plasma level of MCP-1 was measured and then compared between these two groups.</p><p><b>RESULTS</b>The plasma level of MCP-1 in the study group was(257.79±86.52)pg/ml,which was significantly higher than that in control group [(136.57±48.84)pg/ml](P<0.001).</p><p><b>CONCLUSION</b>There may be a correlation between plasma MCP-1 level and AAD.</p>